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Copper Tripeptide-1
Copper Tripeptide-1 (GHK-Cu)
Bioactive copper peptide · dermal papilla activator
Activates dermal papilla cells — the cells that control hair growth — through growth factor signaling pathways. Stimulates fibroblast proliferation and supports VEGF production for blood supply to the follicle.*
Studied in clinical research for follicle activation, growth phase induction, and dermal sheath collagen support. Topical bioavailability lets copper accumulate directly where hair grows.
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Acetyl Tetrapeptide-3
Acetyl Tetrapeptide-3
Synthetic peptide · follicle anchoring
Engineered peptide that supports the proteins anchoring hair to the dermal sheath. Increases Type III collagen and laminin expression in cultured follicle cells, strengthening the foundation that holds hair in place.*
24-week clinical research demonstrates acetyl tetrapeptide-3 supports type III collagen and laminin synthesis in the dermal sheath — the structural proteins that anchor hair more securely in the follicle.
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Rosemary Leaf Extract
Rosemary Leaf Extract
Rosmarinus officinalis · carnosic acid standardized
Carnosic acid activates TRPA1 receptors on scalp sensory neurons, triggering tissue regeneration signaling. Provides antioxidant defense to follicles and supports a balanced scalp microenvironment.*
Mechanistic research identifies rosemary’s carnosic acid as a natural 5α-reductase inhibitor and antioxidant at the follicle, supporting hair density while reducing scalp irritation.
Caffeine
Methylxanthine · follicle metabolic activator
Blocks adenosine receptors in follicle cells, raising cellular energy (cAMP) and IGF-1 expression. Counteracts DHT-induced growth suppression. Penetrates the follicle in roughly 20 minutes and accumulates at 10x the concentration of surrounding skin.*
Pharmacokinetic studies show topical caffeine penetrates the scalp within minutes, where it inhibits phosphodiesterase and extends the anagen (growth) phase of the hair cycle.
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Bacillus Ferment
Bacillus Ferment
Fermentation-derived postbiotic · dermal papilla support
Fermentation by beneficial bacteria yields bioactive peptides (including AC2) that activate Akt/ERK/GSK-3β signaling in dermal papilla cells. The AC2 peptide has been shown to rescue follicle cells stressed by DHT exposure.*
Postbiotic research shows fermentation-derived peptides activate growth-signaling pathways (Akt/ERK) in dermal papilla cells and protect follicles from DHT-driven stress.
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Saccharomyces Ferment
Saccharomyces Ferment Filtrate
Postbiotic · scalp microbiome balancer
A postbiotic (fermentation byproduct, not live bacteria) that supports the scalp's resident beneficial flora and barrier function. Delivers peptides and polysaccharides that hydrate and protect the scalp microenvironment.*
28-day clinical study showed significant increases in beneficial scalp bacteria and reduction in inflammatory organisms, with 100% of participants reporting symptom relief from sensitive scalp.
Biotin (Topical)
Vitamin B7 · keratin cofactor
An essential cofactor your scalp uses to build keratin — the structural protein that makes up 95% of the hair shaft. Topical biotin complements systemic intake by delivering it directly to the surface where keratin synthesis happens.*
Included as a supportive cofactor to ensure adequate biotin availability at the follicle surface during keratin synthesis.